Description

Methyl 4-Chloro-3-Fluorobenzoate is a high-purity fluorinated aromatic ester serving as a critical building block in advanced organic synthesis. This compound matters for its role in introducing the 4-chloro-3-fluorophenyl moiety into target molecules, enabling the development of compounds with tailored biological and physical properties. It is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for creating active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine and chlorine substituents enhance bioactivity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Employed in the research and development of organic semiconductors and charge-transport materials.
• Chemical Research & Development: A versatile building block for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Dye and Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments.

Basic Information

Product Name	Methyl 4-Chloro-3-Fluorobenzoate
CAS No.	206362-87-0
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	4-Chloro-3-fluorobenzoic acid methyl ester; Methyl 4-chloro-3-fluorobenzoate; Benzoic acid, 4-chloro-3-fluoro-, methyl ester; 3-Fluoro-4-chlorobenzoic acid methyl ester; Methyl 3-fluoro-4-chlorobenzoate; 206362-87-0; Methyl p-chloro-m-fluorobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 4-Chloro-3-Fluorobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for demanding synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.