Description

Benzoic Acid, 5-Amino-2,3,4-Trifluoro- (9Ci) is a fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its unique trifluoro-substituted benzoic acid scaffold, which is crucial for modulating the physicochemical properties of target molecules. It is primarily needed by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, where its specific substitution pattern can enhance metabolic stability, bioavailability, and binding affinity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved lipophilicity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), influencing charge transport and emission properties.
• Polymer & Resin Modifier: Incorporated as a monomer or additive to create specialty polymers with enhanced chemical resistance, thermal stability, and surface properties.
• Complex Ligand & Catalyst Development: Employed in organometallic chemistry to synthesize novel chelating ligands and catalysts for asymmetric synthesis and cross-coupling reactions.
• Dye & Pigment Intermediate: Acts as a building block for synthesizing specialized fluorinated dyes and pigments with unique color fastness and spectral characteristics.

Basic Information

Product Name	Benzoic Acid, 5-Amino-2,3,4-Trifluoro- (9Ci)
CAS No.	203916-57-8
Molecular Formula	C7H4F3NO2
Molecular Weight	191.11 g/mol
Synonyms	5-Amino-2,3,4-trifluorobenzoic Acid; 2,3,4-Trifluoro-5-aminobenzoic Acid; 5-Amino-2,3,4-trifluorobenzoic acid (9CI); Benzoic acid, 5-amino-2,3,4-trifluoro-; 5-Amino-2,3,4-trifluoro-benzoic acid; 203916-57-8; 5-Amino-2,3,4-trifluorobenzoic acid (9CI)
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 5-Amino-2,3,4-Trifluoro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.