Description

2,4-Pentadienoic Acid, 5-[4-(Trifluoromethyl)Phenyl]-, (2E,4E)- is a specialized organic compound featuring a conjugated dienoic acid backbone substituted with a trifluoromethylphenyl group. This unique structure makes it a valuable high-purity building block for advanced chemical synthesis, particularly in the development of novel active pharmaceutical ingredients and functional materials. It is primarily sought by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in cutting-edge organic and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug candidates, especially those targeting specific biological pathways where the trifluoromethyl group enhances metabolic stability and binding affinity.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products, leveraging its unique structural motifs to create compounds with specific pesticidal or herbicidal activity.
• Material Science: Acts as a monomer or functionalizing agent in the creation of advanced polymers, coatings, or liquid crystals, where the conjugated system and fluorinated aromatic ring can impart desired electronic or physical properties.
• Organic Synthesis Building Block: Employed in Diels-Alder reactions, Michael additions, and other cyclization or coupling reactions to construct complex polycyclic or heterocyclic frameworks in academic and industrial R&D.
• Fluorine Chemistry Studies: Provides a model compound for investigating the influence of the trifluoromethyl group on reaction kinetics, molecular conformation, and electronic characteristics in organic molecules.

Basic Information

Product Name	2,4-Pentadienoic Acid, 5-[4-(Trifluoromethyl)Phenyl]-, (2E,4E)-
CAS No.	203722-39-8
Molecular Formula	C12H9F3O2
Molecular Weight	242.19 g/mol
Synonyms	(2E,4E)-5-[4-(Trifluoromethyl)phenyl]penta-2,4-dienoic acid; 5-(4-Trifluoromethylphenyl)-2,4-pentadienoic acid; α-(4-Trifluoromethylcinnamylidene)acetic acid; (E,E)-5-(4-Trifluoromethylphenyl)penta-2,4-dienoic acid; 2,4-Pentadienoic acid, 5-[4-(trifluoromethyl)phenyl]-, (2E,4E)-; 4-Trifluoromethylcinnamylideneacetic acid
EINECS	Contact for details

Quality Control

We supply this compound as a high-purity research-grade material. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. Quality is assured through modern analytical techniques including HPLC, GC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.