Description

4-Bromo-2-Chloro-5-Fluorobenzoyl Chloride is a high-purity, multi-halogenated benzoyl chloride derivative serving as a critical building block in advanced organic synthesis. Its value lies in its reactive acid chloride group and strategically placed halogen atoms, which enable precise functionalization for creating complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, especially those requiring halogenated aromatic cores for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the halogen pattern influences selectivity and potency.
• Ligand and Material Science: Building block for creating specialized ligands for catalysis and monomers for high-performance polymers.
• Custom Synthesis & Contract Research: A valuable reagent for custom synthesis houses and R&D laboratories focused on fluorinated and halogenated compound libraries.
• Chemical Research: Employed in academic and industrial research for studying reaction mechanisms and developing new synthetic methodologies involving acyl halides.

Basic Information

Item	Details
Product Name	4-Bromo-2-Chloro-5-Fluorobenzoyl Chloride
CAS No.	203302-93-6
Molecular Formula	C7H2BrCl2FO
Molecular Weight	271.90 g/mol
Synonyms	4-Bromo-2-chloro-5-fluorobenzoic acid chloride; 2-Chloro-4-bromo-5-fluorobenzoyl chloride; 5-Fluoro-4-bromo-2-chlorobenzoyl chloride; Benzoic acid, 4-bromo-2-chloro-5-fluoro-, chloride; 203302-93-6; 4-Bromo-2-chloro-5-fluorobenzoic acid chloride; 4-Bromo-2-chloro-5-fluorobenzoyl chloride
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Chloro-5-Fluorobenzoyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.