Description

Seclazone CAS NO 29050-11-1 is a high-purity pharmaceutical intermediate and research chemical belonging to the benzothiadiazine class. This compound is of significant interest for its role in the synthesis of novel therapeutic agents, particularly in cardiovascular and diuretic research. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced diuretic and antihypertensive drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new benzothiadiazine derivatives.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of target molecules.
• Biochemical Research: Investigated for its interaction with specific ion channels and transporters in physiological studies.

Basic Information

Product Name	Seclazone
CAS No.	29050-11-1
Molecular Formula	C11H11ClN2O3S2
Molecular Weight	318.80 g/mol
Synonyms	7-Chloro-2H-1,2,4-benzothiadiazine-3-carboxylic acid 1,1-dioxide; 7-Chloro-1,2,4-benzothiadiazine-3-carboxylic acid 1,1-dioxide; Seclazone; 7-Chloro-3-carboxy-1,2,4-benzothiadiazine 1,1-dioxide; 29050-11-1; 7-Chloro-1,1-dioxo-1,2,4-benzothiadiazine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our Seclazone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and stringent control of residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.