Description

2-Hydroxy Probenacid is a key organic intermediate and derivative of probenecid, characterized by the introduction of a hydroxyl group. This modification is crucial for enhancing solubility and altering pharmacokinetic properties, making it a valuable building block in advanced pharmaceutical synthesis. It is primarily sought by research institutions and manufacturers in the life sciences sector for developing new therapeutic agents and diagnostic tools.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting renal transport and uric acid excretion pathways.
• Biochemical Research: Used as a reference standard or inhibitor in studies involving organic anion transporters (OATs) and metabolic processes.
• API Development: Employed in the research and development of active pharmaceutical ingredients (APIs) with modified bioavailability and metabolic profiles.
• Metabolite Standard: Acts as a characterized metabolite or analog of probenecid for analytical method development and validation in pharmacokinetic studies.

Basic Information

Product Name	2-Hydroxy Probenacid
CAS No.	28242-02-6
Molecular Formula	C13H19NO5S
Molecular Weight	301.36 g/mol
Synonyms	2-Hydroxyprobenecid; 4-[(Dipropylamino)sulfonyl]benzoic Acid, 2-Hydroxy-; Benzoic acid, 4-[(dipropylamino)sulfonyl]-2-hydroxy-; Probenecid, 2-Hydroxy-; Probenecid Metabolite; 2-OH Probenecid; O-Desmethyl Probenecid (related isomer).
EINECS	Contact for details

Quality Control

Our 2-Hydroxy Probenacid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-grade standards suitable for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.