Description

4-(2,2,2-Trifluoroethoxy)Benzoic Acid is a high-value fluorinated aromatic building block, prized for its unique combination of a benzoic acid core and a trifluoroethoxy substituent. This structure is critical for imparting enhanced metabolic stability, lipophilicity, and bioavailability in advanced molecular design. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in areas requiring fluorinated motifs for improved pharmacokinetics.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the trifluoroethoxy group enhances biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, altering their surface properties and chemical resistance.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, esterifications, and amide formations to create complex fluorinated molecules for various R&D applications.

Basic Information

Product Name	4-(2,2,2-Trifluoroethoxy)Benzoic Acid
CAS No.	27914-56-3
Molecular Formula	C9H7F3O3
Molecular Weight	220.14 g/mol
Synonyms	Benzoic acid, 4-(2,2,2-trifluoroethoxy)-; p-(2,2,2-Trifluoroethoxy)benzoic acid; 4-(Trifluoroethoxy)benzoic acid; 2,2,2-Trifluoroethyl 4-carboxyphenyl ether; 4-Carboxyphenyl 2,2,2-trifluoroethyl ether
EINECS	Contact for details

Quality Control

Every batch of 4-(2,2,2-Trifluoroethoxy)Benzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.