Description

6α-[[[(2-Amino-2,3-Dihydro-1H-Inden)-2-Yl]Carbonyl]Amino]Penicillanic Acid is a specialized β-lactam intermediate with a unique indane-derived side chain. This compound matters as a critical building block for the research and development of novel semi-synthetic penicillins and β-lactamase inhibitors, offering a pathway to enhanced antimicrobial activity profiles. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on advanced antibiotic synthesis and medicinal chemistry.

Application

• Key intermediate in the synthesis of novel penicillin derivatives with potential for improved efficacy.
• Research and development of new β-lactamase inhibitor candidates to combat antibiotic resistance.
• Building block for medicinal chemistry programs targeting bacterial infections.
• Production of non-classical β-lactam compounds for biological evaluation.
• Reference standard for analytical method development and quality control in pharmaceutical manufacturing.
• Starting material for custom synthesis services in fine chemical and contract research organizations (CROs).

Basic Information

Product Name	6α-[[[(2-Amino-2,3-Dihydro-1H-Inden)-2-Yl]Carbonyl]Amino]Penicillanic Acid
CAS No.	27521-60-4
Molecular Formula	C22H23N3O4S
Molecular Weight	425.50 g/mol
Synonyms	6-[(2-Amino-2,3-dihydro-1H-inden-2-yl)formamido]penicillanic acid; (2S,5R,6R)-6-[[(2-Amino-2,3-dihydro-1H-inden-2-yl)carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 6-APA indane derivative; 6β-(2-Aminoindan-2-ylcarboxamido)penicillanic acid; Penicillanic acid, 6-[[(2-amino-2,3-dihydro-1H-inden-2-yl)carbonyl]amino]-
EINECS	Contact for details

Quality Control

Our 6α-[[[(2-Amino-2,3-Dihydro-1H-Inden)-2-Yl]Carbonyl]Amino]Penicillanic Acid is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.