Description

6α-[[(1-Amino-3-Cyclopenten-1-Yl)Carbonyl]Amino]Penicillanic Acid is a key semi-synthetic intermediate in the development of advanced β-lactam antibiotics. This compound is valued for its role in creating novel penicillins with enhanced activity profiles and resistance to β-lactamase enzymes. It is primarily utilized by pharmaceutical research and development teams, as well as manufacturers in the fine chemical sector, for the synthesis of next-generation antibacterial agents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel penicillin and β-lactam antibiotic derivatives.
• Antibacterial Research: Used in medicinal chemistry programs to develop new compounds with activity against resistant bacterial strains.
• Fine Chemical Synthesis: Serves as a specialized intermediate in multi-step organic syntheses for high-value active pharmaceutical ingredients (APIs).
• Biochemical Studies: Employed in research to study the structure-activity relationships (SAR) of β-lactam compounds and their interaction with bacterial enzymes.

Basic Information

Product Name	6α-[[(1-Amino-3-Cyclopenten-1-Yl)Carbonyl]Amino]Penicillanic Acid
CAS No.	27281-85-2
Molecular Formula	C14H19N3O4S
Molecular Weight	325.38 g/mol
Synonyms	6-[(1-Amino-3-cyclopenten-1-yl)carbonyl]amino]penicillanic acid; 6-APA derivative; (2S,5R,6R)-6-[[(1-Amino-3-cyclopenten-1-yl)carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 6-ACA Cyclopentenyl Derivative; Penicillanic Acid, 6-[(1-amino-3-cyclopenten-1-yl)carbonyl]amino]-; 6-ACA Amide Analog
EINECS	Contact for details

Quality Control

Our 6α-[[(1-Amino-3-Cyclopenten-1-Yl)Carbonyl]Amino]Penicillanic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.