Description

Pifexole CAS NO 27199-40-2 is a high-purity chemical compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or active pharmaceutical ingredient (API) in the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) and other specialized medications. Our supply guarantees the consistency and purity required for stringent R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of proprietary drug candidates targeting neurological pathways.
• Active Pharmaceutical Ingredient (API): Serves as the core active component in formulated drug products under development.
• Biochemical Research: Used in vitro and in vivo studies to investigate receptor interactions and pharmacological effects.
• Reference Standard: Employed as a high-purity analytical standard for method development, validation, and quality control testing.
• Preclinical Development: Essential for toxicity studies, pharmacokinetic profiling, and formulation development during drug discovery.

Basic Information

Item	Detail
Product Name	Pifexole
CAS No.	27199-40-2
Molecular Formula	C9H12N2O
Molecular Weight	164.20 g/mol
Synonyms	Pifexole; 2-Amino-6-propyl-4,5,6,7-tetrahydro-1,3-benzoxazole; 6-Propyl-4,5,6,7-tetrahydro-1,3-benzoxazol-2-amine; Pifexolum; U-43,465F; Abbott-43326; 27199-40-2
EINECS	Contact for details

Quality Control

Our Pifexole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identity confirmation via spectroscopic methods. We provide Certificates of Analysis (COA) with full traceability, ensuring compliance with cGMP guidelines for pharmaceutical intermediates. Specifications are aligned with ICH Q3A/B guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Long-term storage under inert atmosphere (e.g., nitrogen) is recommended for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.