Description

Polycytidylic Acid (5') Potassium Salt is a high-purity polynucleotide derivative, specifically the potassium salt of polycytidylic acid. This compound is a critical reagent in molecular biology and biochemical research, serving as a synthetic RNA homopolymer. It is essential for researchers and manufacturers in the life sciences sector who require a reliable and well-characterized substrate for enzymatic studies, hybridization experiments, and the development of diagnostic assays.

Application

• Molecular Biology Research: Used as a template or primer in enzymatic reactions with RNA-dependent polymerases like reverse transcriptase.
• Hybridization Studies: Acts as a synthetic RNA standard in Northern blotting and other nucleic acid hybridization techniques to study gene expression.
• Biochemical Assay Development: Employed in the research and quality control of diagnostic kits that detect RNA viruses or specific RNA sequences.
• Enzymology: Serves as a substrate for studying the activity, kinetics, and inhibition of ribonucleases and other RNA-processing enzymes.
• Cell Culture & Virology: Used in research applications to stimulate immune responses or as a model for viral RNA in experimental systems.
• Pharmaceutical R&D: Investigated for potential use in vaccine adjuvants, immunotherapies, and as a component in novel drug delivery systems.

Basic Information

Product Name	Polycytidylic Acid (5') Potassium Salt
CAS No.	26936-40-3
Molecular Formula	(C9H12KN3O8P)n
Molecular Weight	~323.28 (monomer) * n
Synonyms	Poly(C) Potassium Salt; Polycytidylic Acid Potassium Salt; 5'-Polycytidylic Acid Potassium Salt; Potassium Polycytidylate; Poly rC Potassium Salt; Cytidine Homopolymer Potassium Salt; Polycytidylate (Potassium); Polycytidylic Acid, Potassium Salt
EINECS	Contact for details

Quality Control

Our Polycytidylic Acid (5') Potassium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including spectroscopic identification, purity assessment by HPLC, and quantification of residual solvents and endotoxins where applicable. A Certificate of Analysis (COA) detailing specific results for identity, assay, and impurities is provided to ensure compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate at -20°C. Allow the container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95% (Polycytidylic Acid basis)
pH (1% Solution)	6.0 - 8.0
Absorbance Ratio (A250/A260)	0.40 - 0.50
Absorbance Ratio (A280/A260)	1.70 - 1.90
Water Content (KF)	≤ 5.0 %
Endotoxin (LAL)	< 10 EU/mg (if specified)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.