Description

L-Amoxicillin CAS NO 26889-93-0 is a high-purity, semi-synthetic penicillin antibiotic belonging to the aminopenicillin class. It is a critical active pharmaceutical ingredient (API) valued for its broad-spectrum bactericidal activity against a wide range of Gram-positive and Gram-negative bacteria. This compound is essential for pharmaceutical manufacturers in the production of various antibiotic formulations, including oral capsules, tablets, and sterile injectables. Its reliable quality and consistent performance are paramount for ensuring the efficacy and safety of the final medicinal products.

Application

• Pharmaceutical API: Primary use as the active ingredient in the synthesis of amoxicillin-based antibiotic drugs.
• Oral Dosage Forms: Manufacturing of capsules, tablets, and oral suspensions for treating bacterial infections.
• Sterile Injectable Formulations: Production of parenteral solutions for hospital and clinical use.
• Veterinary Pharmaceuticals: Used in antibiotic preparations for treating bacterial infections in animals.
• Research & Development: Serves as a reference standard and key intermediate in pharmaceutical R&D for new antibiotic studies.
• Combination Therapies: Used in fixed-dose combination drugs, such as amoxicillin/clavulanate potassium preparations.

Basic Information

Product Name	L-Amoxicillin
CAS No.	26889-93-0
Molecular Formula	C₁₆H₁₉N₃O₅S
Molecular Weight	365.40 g/mol
Synonyms	Amoxicillin; (2S,5R,6R)-6-[[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; D-(-)-α-Amino-p-hydroxybenzylpenicillin; Amoxicilline; Amoxycillin; Amoxil; Larotid; Polymox; Trimox; Wymox
EINECS	248-003-8

Quality Control

Our L-Amoxicillin is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP, EP, and BP. Every batch undergoes comprehensive analytical testing, including identification, assay, impurity profiling, and residual solvent analysis. A Certificate of Analysis (COA) detailing all test results is provided to ensure full traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Specific Optical Rotation	+290° to +315° (c=0.1 in water)
Heavy Metals	≤ 20 ppm
Microbial Limits	Conforms to EP/ USP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.