Description

Carbenicillin Indanyl Sodium is a semi-synthetic, β-lactamase-resistant penicillin antibiotic prodrug. Its primary value lies in its enhanced oral bioavailability compared to the parent carbenicillin, making it a critical intermediate in pharmaceutical synthesis. This compound is essential for manufacturers and research institutions developing or producing oral antibiotic formulations, particularly for treating infections caused by susceptible Gram-negative bacteria.

Application

• Pharmaceutical Active Pharmaceutical Ingredient (API): Primary use as the key intermediate in the synthesis of oral carbenicillin prodrug formulations.
• Antibiotic Drug Manufacturing: Serves as a crucial raw material for producing finished dosage forms, such as tablets and capsules, for systemic antibiotic therapy.
• Microbiological Research: Used in laboratory settings to study antibiotic resistance mechanisms, particularly those involving β-lactamases.
• Veterinary Medicine: Applied in the development of antibacterial treatments for veterinary use, targeting specific bacterial infections in animals.
• Reference Standard: Utilized as a high-purity chemical standard in quality control laboratories for HPLC, LC-MS, or pharmacopeial testing of related pharmaceutical products.

Basic Information

Product Name	Carbenicillin Indanyl Sodium
CAS No.	26605-69-6
Molecular Formula	C26H26N2Na2O6S
Molecular Weight	528.5 g/mol
Synonyms	Carbenicillin Indanyl Sodium Salt; Indanyl Carbenicillin Sodium; Carindacillin Sodium; (2S,5R,6R)-6-[(Carboxy)(phenyl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid indan-5-yl ester sodium salt; Sodium (2S,5R,6R)-6-[(phenyl)(carboxy)formamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate indan-5-yl ester; Geopen Oral; Urobac
EINECS	Contact for details

Quality Control

Our Carbenicillin Indanyl Sodium is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC, to ensure it meets stringent specifications for pharmaceutical use. Certificates of Analysis (COA) are provided with each shipment, detailing compliance with relevant internal and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. Recommended long-term storage temperature is 2-8°C (refrigerated).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
pH (1% Solution)	5.5 - 7.5
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.