Description

Sodium 4-Trifluoromethylbenzoate is the sodium salt derivative of 4-(trifluoromethyl)benzoic acid, a key fluorinated aromatic building block. This compound is valued for its role as a versatile intermediate in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors where the trifluoromethyl group imparts desirable metabolic stability and lipophilicity. It is essential for research chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially those containing the bioisosteric trifluoromethyl group.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine moiety enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers to alter surface properties, chemical resistance, and thermal stability.
• Organic Synthesis Reagent: Acts as a stable, soluble carboxylate source in various coupling reactions and nucleophilic substitutions in research and development.
• Coordination Chemistry & Ligand Synthesis: Useful for preparing carboxylate-based ligands for metal-organic frameworks (MOFs) and catalysts.

Basic Information

Product Name	Sodium 4-Trifluoromethylbenzoate
CAS No.	25832-58-0
Molecular Formula	C8H4F3NaO2
Molecular Weight	212.10 g/mol
Synonyms	4-(Trifluoromethyl)benzoic acid sodium salt; Benzoic acid, 4-(trifluoromethyl)-, sodium salt; Sodium α,α,α-trifluoro-p-toluate; p-Trifluoromethylbenzoic acid sodium salt; Sodium p-trifluoromethylbenzoate; TFMBA sodium salt; NaTFMBA
EINECS	Contact for details

Quality Control

Our Sodium 4-Trifluoromethylbenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets precise customer specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring traceability and compliance for your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent caking or decomposition. Keep away from incompatible materials such as strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Heavy Metals (as Pb)	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.