Description

Poly(Xanthylic Acid) is a synthetic polynucleotide derivative, specifically a homopolymer of xanthosine monophosphate. This compound is a critical biochemical reagent used in research to study nucleic acid structure, function, and enzymatic interactions. It serves as a valuable tool for scientists in molecular biology, enzymology, and pharmaceutical development. Its defined polymeric structure makes it essential for applications requiring specific nucleotide sequences or analogs.

Application

• Biochemical Research: Used as a substrate or template in enzymatic studies, particularly for polymerases, nucleases, and phosphorylases.
• Molecular Biology: Serves as a model polynucleotide for investigating RNA structure, stability, and hybridization properties.
• Pharmaceutical Development: Employed in the research and screening of antiviral and anticancer agents that target nucleic acid metabolism.
• Diagnostic Assay Development: Can be utilized in the design and calibration of diagnostic kits that detect or quantify specific enzymatic activities.
• Enzyme Kinetics: Acts as a standard or control in kinetic assays to determine enzyme activity and inhibition constants.
• Academic & Industrial R&D: A fundamental reagent for universities and biotech companies exploring novel therapeutic targets and genetic mechanisms.

Basic Information

Product Name	Poly(Xanthylic Acid)
CAS No.	25249-23-4
Molecular Formula	(C10H12N4O9P)n
Molecular Weight	Variable (Polymer)
Synonyms	Poly(Xanthylic acid); Poly(XMP); Polyxanthylic acid; Polynucleotide (xanthylic acid); Xanthosine homopolymer; Polyxanthylate; Poly(Xanthosine 5'-monophosphate); Poly(5'-XMP)
EINECS	Contact for details

Quality Control

Our Poly(Xanthylic Acid) is produced and tested to meet the stringent requirements of life science research. Each batch undergoes rigorous analytical characterization to ensure purity, chain length consistency, and functional integrity. Standard quality parameters include assessment by HPLC, UV spectroscopy, and enzymatic digest analysis. A comprehensive Certificate of Analysis (COA) detailing purity, absorbance ratios, and physical state is provided with every shipment to guarantee traceability and performance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). For long-term storage, desiccate and keep frozen. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (UV)	Conforms to reference spectrum
Purity (HPLC)	≥ 95% (Polymer Fraction)
A260/A280 Ratio	2.0 - 2.2 (in buffer)
Solubility	Soluble in aqueous buffers, alkaline solutions
Chain Length (Average)	Specified per grade (e.g., n=10-50)
Moisture Content (KF)	≤ 5.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.