Description

2'-Deoxyadenylyl-(3'-5')-2'-Deoxyadenylyl-(3'-5)-2'-Deoxyadenosine is a defined trinucleotide, specifically a deoxyadenosine trimer, with the CAS number 25138-00-5. This high-purity biochemical is critical for research and development in molecular biology and nucleic acid chemistry, serving as a precise building block or reference standard. It is primarily needed by biotechnology companies, academic research institutions, and pharmaceutical developers working on oligonucleotide synthesis, diagnostic assay development, and fundamental studies of DNA structure and function.

Application

• Oligonucleotide Synthesis: Used as a controlled intermediate or reference standard in the solid-phase synthesis of longer DNA strands.
• Biochemical Research: Serves as a substrate or model compound in enzymatic studies involving nucleases, ligases, and polymerases.
• Diagnostic Development: Acts as a key component in the development and calibration of molecular diagnostic probes and assays.
• Pharmaceutical R&D: Employed in early-stage research for antisense oligonucleotides, aptamers, and other therapeutic nucleic acid platforms.
• Quality Control & Standardization: Functions as an analytical reference standard for purity and identity verification of oligonucleotide products.
• Academic Studies: Utilized in university laboratories for teaching and research on DNA biochemistry and molecular interactions.

Basic Information

Product Name	2'-Deoxyadenylyl-(3'-5')-2'-Deoxyadenylyl-(3'-5)-2'-Deoxyadenosine
CAS No.	25138-00-5
Molecular Formula	C30H37N15O18P2
Molecular Weight	917.66 g/mol
Synonyms	d(ApApA); Deoxyadenosine Trimer; d(A)3; 2'-Deoxyadenylyl-(3'→5')-2'-deoxyadenylyl-(3'→5')-2'-deoxyadenosine; Adenine oligonucleotide d(pApApA); Trinucleotide d(ApApA); pd(ApApA); Oligodeoxyadenylic acid trimer
EINECS	Contact for details

Quality Control

Our 2'-Deoxyadenylyl-(3'-5')-2'-Deoxyadenylyl-(3'-5)-2'-Deoxyadenosine is produced under stringent conditions to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous internal quality standards and can support development under cGMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a dry atmosphere before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (UV)	Conforms
Purity (HPLC)	≥ 95%
Assay	≥ 85% (by UV)
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.