Description

3-Chloro-5-Fluorobenzoic Acid is a high-purity halogenated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its value lies in its dual functionalization, providing a versatile scaffold for constructing complex molecules in regulated industries. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical sectors who require reliable, high-quality intermediates for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators, leveraging the bioactivity of the halogenated aromatic ring.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing fluorinated and chlorinated aromatic cores essential for electronic materials with specific dielectric and luminescent properties.
• Polymer Modification: Employed to introduce halogenated benzoate groups into polymer chains, enhancing material properties like flame retardancy and chemical resistance.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to create complex, multi-substituted arenes.
• Chemical Research & Development: A valuable reference standard and starting material in academic and industrial R&D labs for exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	3-Chloro-5-Fluorobenzoic Acid
CAS No.	25026-64-6
Molecular Formula	C7H4ClFO2
Molecular Weight	174.56 g/mol
Synonyms	5-Fluoro-3-chlorobenzoic Acid; Benzoic acid, 3-chloro-5-fluoro-; 3-Chloro-5-fluorobenzoic acid; 3-Chloro-5-fluoro-benzoic acid; 25026-64-6; 3-Cl-5-F-BA
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Fluorobenzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the stringent requirements of our global customer base. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.