Description

Mono(4-Aminophenyl)-3'-Thymidylic Acid Ester is a specialized nucleotide derivative that serves as a critical building block in advanced biochemical synthesis. This compound matters for its role as a key intermediate in the production of oligonucleotides and modified nucleic acids, enabling precise molecular design. It is primarily needed by research institutions and pharmaceutical companies engaged in drug discovery, molecular diagnostics, and the development of antisense therapies.

Application

• Oligonucleotide Synthesis: A vital phosphoramidite precursor for the solid-phase synthesis of DNA and RNA strands.
• Antisense Drug Development: Used in creating modified oligonucleotides for therapeutic applications targeting specific genes.
• Molecular Probe Fabrication: Essential for manufacturing labeled probes used in diagnostic assays and hybridization techniques.
• Bioconjugation: The reactive amino group facilitates conjugation with other molecules, such as fluorophores or peptides, for creating complex bioconjugates.
• Academic & Industrial Research: A key reagent in biochemical research for studying nucleic acid structure, function, and interactions.

Basic Information

Product Name	Mono(4-Aminophenyl)-3'-Thymidylic Acid Ester
CAS No.	24960-61-0
Molecular Formula	C16H19N3O7
Molecular Weight	365.34 g/mol
Synonyms	4-Aminophenyl Thymidine 3'-Monophosphate Ester; 3'-(4-Aminophenyl phosphate) Thymidine; Thymidine 3'-(4-aminophenyl phosphate); 5'-O-DMT-3'-(4-Aminophenyl phosphate) Thymidine (protected form); 4-Aminophenyl Thymidylate; Nucleotide-Aminophenyl Conjugate; p-Aminophenyl Thymidine 3'-Phosphate Ester
EINECS	Contact for details

Quality Control

Our Mono(4-Aminophenyl)-3'-Thymidylic Acid Ester is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.