Description

n-Carboxymethylisatoic Anhydride is a specialized heterocyclic building block and reactive intermediate of significant interest in advanced organic synthesis. Its core value lies in its bifunctional reactivity, combining an anhydride moiety with a carboxymethyl group, enabling the construction of complex molecular architectures. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of quinazoline and quinazolinone derivatives, which are important scaffolds in drug discovery for anticancer, antimicrobial, and kinase inhibitor applications.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators that incorporate the isatoic anhydride core.
• Dye and Pigment Manufacturing: Serves as a precursor for the production of specialized heterocyclic dyes and functional colorants.
• Polymer Modification: Employed as a reactive monomer or cross-linking agent to introduce carboxylic acid functionality and aromatic character into polymer chains, enhancing material properties.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for high-throughput screening.

Basic Information

Item	Details
Product Name	n-Carboxymethylisatoic Anhydride
CAS No.	24648-52-0
Molecular Formula	C10H7NO5
Molecular Weight	221.17 g/mol
Synonyms	2-Carboxymethylisatoic Anhydride; 1H-3,1-Benzoxazine-2,4(5H)-dione, 3-(carboxymethyl)-; 3-(Carboxymethyl)-1H-3,1-benzoxazine-2,4(5H)-dione; N-Carboxymethylanthranilic Acid Cyclic Anhydride; Isatoic Anhydride, N-carboxymethyl-; Anthranilic Acid N-(carboxymethyl) Anhydride
EINECS	Contact for details

Quality Control

Our n-Carboxymethylisatoic Anhydride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes data from HPLC, NMR, and IR spectroscopy. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.