Description

2-Formyl-4-(Trifluoromethyl)Benzoic Acid is a versatile and high-value trifluoromethylated aromatic building block, essential for advanced organic synthesis. Its unique structure, combining a formyl group and a carboxylic acid function on a trifluoromethylated benzene ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system, inflammation, and oncology, where the trifluoromethyl group enhances metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl moiety contributes to improved biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated chelating ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the synthesis of specialty monomers and polymers, such as polyimides or liquid crystals, where the introduction of fluorine atoms can modify thermal stability, optical properties, and chemical resistance.
• Fluorescent Dye and Sensor Fabrication: Acts as a core building block for synthesizing advanced fluorophores and molecular sensors used in bio-imaging and diagnostic applications.

Basic Information

Product Name	2-Formyl-4-(Trifluoromethyl)Benzoic Acid
CAS No.	23984-83-0
Molecular Formula	C9H5F3O3
Molecular Weight	218.13 g/mol
Synonyms	4-(Trifluoromethyl)phthalaldehyde-2-carboxylic acid; 2-Carboxy-4-(trifluoromethyl)benzaldehyde; 4-(Trifluoromethyl)phthalaldehydic acid; 2-Formyl-4-trifluoromethylbenzoic acid; Benzoic acid, 2-formyl-4-(trifluoromethyl)-; 2-Aldehyde-4-trifluoromethylbenzoic acid; α-Formyl-α-trifluoromethyl-o-phthalic acid (obsolete)
EINECS	Contact for details

Quality Control

Every batch of 2-Formyl-4-(Trifluoromethyl)Benzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.