Description

Cloxacillin Benzathine CAS NO 23736-58-5 is a benzathine salt form of the semisynthetic penicillin antibiotic cloxacillin, designed for enhanced stability and prolonged action. This compound is critical for formulating long-acting veterinary and pharmaceutical injectable suspensions to combat bacterial infections. It is primarily required by manufacturers in the animal health sector and pharmaceutical companies developing depot formulations for human medicine.

Application

• Veterinary Injectable Formulations: Key active ingredient in long-acting intramammary infusions and injectable suspensions for the treatment of mastitis and other bacterial infections in livestock.
• Pharmaceutical Depot Injections: Used in the development of sustained-release human pharmaceutical products requiring prolonged antibiotic serum levels.
• Antibiotic Premix Manufacturing: Incorporated into medicated feed premixes for prophylactic and therapeutic use in animal husbandry.
• Research & Development: Serves as a reference standard and raw material in antimicrobial research and new drug development studies.
• API for Generic Drug Production: Active Pharmaceutical Ingredient (API) for the manufacture of generic antibiotic formulations.

Basic Information

Product Name	Cloxacillin Benzathine
CAS No.	23736-58-5
Molecular Formula	C₃₄H₄₂Cl₂N₆O₈S₂
Molecular Weight	797.77 g/mol
Synonyms	Benzathine Cloxacillin; Cloxacillin Benzathine Salt; (2S,5R,6R)-6-[[3-(2-Chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid compound with N,N'-dibenzylethylenediamine; Cloxacillin DBED Salt; Orbenin DC; BRL 1621 Benzathine; 5-Methyl-3-o-chlorophenyl-4-isoxazolylpenicillin Benzathine
EINECS	Contact for details

Quality Control

Our Cloxacillin Benzathine is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical and veterinary use. A Certificate of Analysis (COA) detailing purity, potency, and impurity profiles is provided with every shipment to guarantee supply reliability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
pH (Suspension)	5.0 - 7.5
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.