Description

p-Nitrophenyl 2-Acetamido-2-Deoxy-α-D-Galactopyranoside is a specialized chromogenic substrate used in enzymatic assays. This compound is critical for the detection and quantification of α-N-acetylgalactosaminidase and related glycosidase enzymes. It is primarily required by researchers and quality control laboratories in the pharmaceutical, diagnostic, and life science research sectors for biochemical analysis and diagnostic kit development.

Application

• Enzymatic Substrate for Glycosidase Assays: Primary substrate for the spectrophotometric measurement of α-N-acetylgalactosaminidase (α-NAGA) activity.
• Diagnostic Reagent Manufacturing: A key raw material in the production of diagnostic kits for inborn errors of metabolism, such as Schindler and Kanzaki diseases.
• Biochemical Research: Used in enzyme kinetics studies, inhibitor screening, and characterization of glycoside hydrolase enzyme specificity.
• Quality Control in Biopharma: Employed in QC labs to monitor enzyme activity during the purification and production of therapeutic proteins.
• Microbiology Studies: Applied in research to study bacterial glycosidases and their role in pathogenesis or carbohydrate metabolism.

Basic Information

Product Name	p-Nitrophenyl 2-Acetamido-2-Deoxy-α-D-Galactopyranoside
CAS No.	23646-68-6
Molecular Formula	C14H18N2O8
Molecular Weight	342.30 g/mol
Synonyms	4-Nitrophenyl N-acetyl-α-D-galactosaminide; p-Nitrophenyl α-D-GalNAc; PNP-α-GalNAc; α-PNP-GalNAc; 4-Nitrophenyl 2-acetamido-2-deoxy-α-D-galactopyranoside; N-Acetyl-α-D-galactosaminide 4-nitrophenyl; 2-Acetamido-2-deoxy-α-D-galactopyranoside 4-nitrophenyl
EINECS	Contact for details

Quality Control

Our p-Nitrophenyl 2-Acetamido-2-Deoxy-α-D-Galactopyranoside is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency suitable for sensitive biochemical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and performance in standard enzymatic assays. We support compliance with relevant GMP and ISO 9001 standards for research and diagnostic use.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Specific Rotation	Contact for details
Enzymatic Activity	Suitable for α-NAGA assay
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.