Description

Potassium [2S-[2Alpha,5Alpha,6Beta(S*)]]-6-(Aminophenylacetamido)-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate is a potassium salt derivative of a penicillin core structure, serving as a crucial high-purity pharmaceutical intermediate for advanced synthesis. This compound is essential for research and development in creating novel β-lactam antibiotics and for precise analytical reference standards. It is primarily required by pharmaceutical manufacturers, contract research organizations (CROs), and academic research laboratories focused on antimicrobial development and chemical synthesis.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: Key intermediate in the production of specialized penicillin and cephalosporin-class antibiotics.
• Research & Development: Used in medicinal chemistry for the design, synthesis, and structure-activity relationship (SAR) studies of new β-lactam compounds.
• Analytical Reference Standard: Serves as a high-purity standard for quality control testing, method development, and validation in pharmaceutical analysis (HPLC, LC-MS).
• Process Chemistry: Employed in scaling up and optimizing synthetic routes for antibiotic manufacturing under GMP conditions.
• Biochemical Research: Tool compound for studying bacterial resistance mechanisms, particularly those involving β-lactamases.

Basic Information

Item	Details
Product Name	Potassium [2S-[2Alpha,5Alpha,6Beta(S*)]]-6-(Aminophenylacetamido)-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate
CAS No.	23277-71-6
Molecular Formula	C16H17KN2O4S
Molecular Weight	372.48 g/mol
Synonyms	Potassium 6-APA derivative; Potassium (2S,5R,6R)-6-[(Aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; 6-APA Potassium Salt (Aminophenylacetyl); Aminobenzylpenicillin Potassium Salt Derivative; Potassium D-α-Aminobenzylpenicillinate; ABPC Potassium Intermediate; Penicillin G Potassium Aminophenyl Analog; Potassium Pharmaceutic Intermediate 23277-71-6
EINECS	Contact for details

Quality Control

Our Potassium [2S-[2Alpha,5Alpha,6Beta(S*)]]-6-(Aminophenylacetamido)-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure high chemical purity and identity, meeting the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) with detailed specifications from HPLC, NMR, and IR are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.