Description

3-[[[2-(4-Methyl-1-Piperazinyl)Ethoxy]Imino]Methyl]Rifamycin is a semi-synthetic derivative of the rifamycin class of antibiotics, representing a key intermediate in the development of advanced antimicrobial agents. This compound matters for its role in creating next-generation antibiotics designed to combat resistant bacterial strains, particularly in the pharmaceutical research and development sector. It is primarily needed by pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in the synthesis of novel anti-tuberculosis and antibacterial drugs.

Application

• Pharmaceutical Intermediate: Critical starting material or intermediate in the synthesis of novel rifamycin-based antibiotics.
• Antibacterial Research: Used in R&D for developing new compounds to address multidrug-resistant tuberculosis (MDR-TB) and other Gram-positive bacterial infections.
• Microbiological Studies: Serves as a reference standard or active component in studies of bacterial RNA polymerase inhibition.
• API Synthesis: Employed in the production pathway for Active Pharmaceutical Ingredients (APIs) targeting specific infectious diseases.

Basic Information

Product Name	3-[[[2-(4-Methyl-1-Piperazinyl)Ethoxy]Imino]Methyl]Rifamycin
CAS No.	22912-78-3
Molecular Formula	C39H51N5O12
Molecular Weight	781.86 g/mol
Synonyms	3-[(Z)-[2-(4-Methylpiperazin-1-yl)ethoxy]iminomethyl]rifamycin SV; 3-Formylrifamycin SV O-[2-(4-methyl-1-piperazinyl)ethyl]oxime; Rifamycin Derivative 22912-78-3; (3-Formylrifamycin SV) 2-(4-Methyl-1-piperazinyl)ethyloxime; Antibiotic Derivative CP 40,000; A semisynthetic rifamycin.
EINECS	Contact for details

Quality Control

Our 3-[[[2-(4-Methyl-1-Piperazinyl)Ethoxy]Imino]Methyl]Rifamycin is manufactured under strict quality systems suitable for pharmaceutical R&D. Products undergo rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure compliance with internal specifications. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after the original container is opened. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Orange-red to brownish-red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.