Description

4'-Fluoro-4-Hydroxy-Biphenyl-3-Carboxylic Acid is a high-purity fluorinated biphenyl derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a carboxylic acid and a phenolic hydroxyl group on a fluorinated biphenyl scaffold, makes it an invaluable intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and advanced materials sectors, where it is used to synthesize active pharmaceutical ingredients (APIs) and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in non-steroidal anti-inflammatory drugs (NSAIDs) and other small molecule therapeutics.
• Liquid Crystal Materials: Serves as a core component in the synthesis of fluorinated liquid crystals for display technologies, leveraging the biphenyl structure and fluorine atom for stability and electro-optical properties.
• Advanced Polymer Synthesis: Used as a monomer or co-monomer to introduce rigidity, thermal stability, and specific functional groups into high-performance engineering plastics and specialty polymers.
• Agrochemical Research: Employed in the research and development of new-generation herbicides and pesticides, where the fluorobiphenyl moiety can enhance biological activity and environmental stability.
• Organic Electronic Materials: Acts as a precursor for materials used in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Chemical Research & Development: A versatile building block for academic and industrial research in medicinal chemistry, materials science, and supramolecular chemistry.

Basic Information

Product Name	4'-Fluoro-4-Hydroxy-Biphenyl-3-Carboxylic Acid
CAS No.	22510-33-4
Molecular Formula	C₁₃H₉FO₃
Molecular Weight	232.21 g/mol
Synonyms	3-Biphenylcarboxylic acid, 4'-fluoro-4-hydroxy-; 4-Hydroxy-4'-fluorobiphenyl-3-carboxylic acid; 4'-Fluoro-4-hydroxy[1,1'-biphenyl]-3-carboxylic acid; 4-Hydroxy-4'-fluorodiphenyl-3-carboxylic acid; 4'-Fluoro-4-hydroxybiphenyl-3-carboxylic acid; 3-Carboxy-4'-fluoro-4-hydroxybiphenyl; [1,1'-Biphenyl]-3-carboxylic acid, 4'-fluoro-4-hydroxy-
EINECS	Contact for details

Quality Control

Every batch of 4'-Fluoro-4-Hydroxy-Biphenyl-3-Carboxylic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, NMR, and IR spectroscopy. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your most critical synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.