Description

3'-Fluoro-4-Hydroxy-Biphenyl-3-Carboxylic Acid is a high-purity fluorinated biphenyl derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring both a carboxylic acid and a phenolic hydroxyl group on a fluorinated biphenyl scaffold, makes it an invaluable building block for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the synthesis of advanced herbicides and fungicides, where the fluorine atom and biphenyl core can enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated biphenyl-based compounds for high-performance liquid crystal displays (LCDs).
• Organic Electronic Materials: Acts as a building block for organic semiconductors and charge-transport materials used in OLEDs and organic photovoltaics.
• Chemical Research & Development: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new synthetic methodologies involving fluorinated aromatics.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis services to produce specialized fine chemicals and target molecules for clients.

Basic Information

Item	Details
Product Name	3'-Fluoro-4-Hydroxy-Biphenyl-3-Carboxylic Acid
CAS No.	22494-43-5
Molecular Formula	C13H9FO3
Molecular Weight	232.21 g/mol
Synonyms	3'-Fluoro-4'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid; 3-(3-Fluoro-4-hydroxyphenyl)benzoic acid; 3-Carboxy-3'-fluoro-4-hydroxybiphenyl; [1,1'-Biphenyl]-3-carboxylic acid, 3'-fluoro-4'-hydroxy-; 3-Fluoro-4-hydroxybiphenyl-3'-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3'-Fluoro-4-Hydroxy-Biphenyl-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements of our global clientele. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.