Description

Hydrocinnamic Acid, α-Fluoro-3,4-Dihydroxy- (8Ci) is a fluorinated derivative of hydrocinnamic acid featuring a dihydroxy substitution pattern. This compound is a valuable fluorinated synthon and intermediate in advanced organic synthesis, prized for its ability to introduce both fluorine and phenolic functionalities into target molecules. It is primarily utilized by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Research: Used in developing novel herbicides and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Ligand Synthesis: Serves as a precursor for chelating agents and catalysts in asymmetric synthesis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: An important substrate for investigating fluorination reactions and the electronic effects of fluorine in aromatic systems.
• Polymer Modification: Intermediate for creating specialty polymers with unique surface properties and stability.
• Biochemical Probe Development: Used to synthesize labeled compounds or probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Hydrocinnamic Acid, α-Fluoro-3,4-Dihydroxy- (8Ci)
CAS No.	22179-94-8
Molecular Formula	C9H9FO3
Molecular Weight	184.16 g/mol
Synonyms	2-Fluoro-3-(3,4-dihydroxyphenyl)propanoic Acid; 3-(3,4-Dihydroxyphenyl)-2-fluoropropanoic Acid; α-Fluoro-3,4-dihydroxyhydrocinnamic Acid; 2-Fluoro-3,4-dihydroxyhydrocinnamic Acid; 3,4-Dihydroxy-α-fluorohydrocinnamic Acid; (2R/S)-2-Fluoro-3-(3,4-dihydroxyphenyl)propanoic Acid (racemic mixture); NSC 403714
EINECS	Contact for details

Quality Control

Every batch of Hydrocinnamic Acid, α-Fluoro-3,4-Dihydroxy- (8Ci) is produced and tested under strict quality management protocols. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical research and development projects. A Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), physical characteristics, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.