Description

Sodium [2S-(2Alpha,5Alpha,6Beta)]-6-[(1,3-Dioxo-3-Phenoxy-2-Phenylpropyl)Amino]-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate is the sodium salt of a semisynthetic penicillin derivative, specifically a penicillinase-resistant penicillin. This compound is a key advanced pharmaceutical intermediate (API intermediate) in the synthesis of certain β-lactam antibiotics. It is primarily utilized by pharmaceutical manufacturers and research institutions for the development and production of specialized antimicrobial agents. The material is supplied with a focus on high purity and consistency to meet stringent pharmaceutical manufacturing requirements.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of penicillinase-resistant penicillin antibiotics.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the final chemical steps to produce specific β-lactam antibiotic APIs.
• Research & Development: Serves as a reference standard and starting material in medicinal chemistry research for novel antibiotic development.
• Process Chemistry: Employed in scale-up and optimization studies for antibiotic manufacturing processes.
• Biochemical Research: Used in studies investigating bacterial resistance mechanisms and the action of β-lactamase inhibitors.

Basic Information

Product Name	Sodium [2S-(2Alpha,5Alpha,6Beta)]-6-[(1,3-Dioxo-3-Phenoxy-2-Phenylpropyl)Amino]-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate
CAS No.	21649-57-0
Molecular Formula	C24H23N2NaO6S
Molecular Weight	478.51 g/mol
Synonyms	Sodium Dicloxacillin; Dicloxacillin Sodium Impurity; Sodium 6-[3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolecarboxamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; BRL 1702 Sodium Salt; Dicloxacillin Sodium Salt; 6-[[[3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Sodium Salt; Stafopenin Sodium; MDI-PC
EINECS	Contact for details

Quality Control

Our Sodium Dicloxacillin intermediate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical synthesis. We provide full traceability and Certificates of Analysis (COA) are supplied with every shipment, detailing key parameters such as assay, related substances, and residual solvents. Our quality commitment aligns with cGMP principles for API intermediate manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.