Description

4,4-Bis(4-Fluorophenyl)Butyric Acid is a high-purity fluorinated aromatic carboxylic acid building block of significant importance in advanced organic synthesis. Its molecular structure, featuring two para-fluorophenyl groups, makes it a critical intermediate for the development of pharmaceuticals and specialty materials. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and liquid crystal industries for creating novel active compounds and functional polymers.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated mesogens, which are essential components in high-performance liquid crystal displays (LCDs).
• Polymer Chemistry: Incorporated as a monomer or chain modifier to produce specialty polymers with enhanced thermal stability, chemical resistance, and specific optical properties.
• Organic Electronic Materials: Investigated for use in the synthesis of organic semiconductors and charge-transport materials for OLEDs and photovoltaic cells.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of compound libraries.

Basic Information

Product Name	4,4-Bis(4-Fluorophenyl)Butyric Acid
CAS No.	20662-52-6
Molecular Formula	C16H14F2O2
Molecular Weight	276.28 g/mol
Synonyms	4,4-Bis(p-fluorophenyl)butyric acid; 4-[Bis(4-fluorophenyl)methyl]butanoic acid; 4,4'-(4-Carboxybutylidene)bis(fluorobenzene); γ-Oxo-4,4-bis(4-fluorophenyl)butane; Butyric acid, 4,4-bis(4-fluorophenyl)-; 4,4-Di(4-fluorophenyl)butanoic acid; 4-(Bis(4-fluorophenyl)methylene)butanoic acid
EINECS	Contact for details

Quality Control

Our 4,4-Bis(4-Fluorophenyl)Butyric Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.