Description

4,5-Difluoro-2-Nitrobenzoic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both nitro and carboxylic acid functional groups on a difluorinated benzene ring, makes it a versatile precursor for creating complex molecules. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific enzyme inhibition or receptor binding.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, liquid crystals, and advanced organic electronic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized fluorinated dyes and pigments with unique color and light-fastness properties.
• Chemical Biology & Proteomics: Acts as a valuable probe or linker molecule in the study of biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global R&D projects.

Basic Information

Product Name	4,5-Difluoro-2-Nitrobenzoic Acid
CAS No.	20372-63-8
Molecular Formula	C7H3F2NO4
Molecular Weight	203.10 g/mol
Synonyms	2-Nitro-4,5-difluorobenzoic Acid; 4,5-Difluoro-2-nitrobenzoic acid; Benzoic acid, 4,5-difluoro-2-nitro-; 4,5-Difluoronitrobenzoic Acid
EINECS	Contact for details

Quality Control

Every batch of 4,5-Difluoro-2-Nitrobenzoic Acid is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee reliable quality and traceability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.