Description

2,5-Difluorobenzoic Acid is a versatile fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its ability to introduce fluorine atoms and a carboxylic acid functional group into target molecules, enabling precise modulation of their physical, chemical, and biological properties. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drugs where the difluoro-substitution pattern can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging the fluorine atoms to improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated components for electronic displays and organic light-emitting diodes, contributing to improved performance and stability.
• Polymer & Resin Modifier: Incorporated as a monomer or additive to create specialty polymers with enhanced chemical resistance, thermal stability, or specific surface properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, esterification, and amide bond formation as a readily derivatizable aromatic acid in research and scale-up laboratories.
• Fluorinated Dye & Pigment Precursor: Acts as a starting material for synthesizing specialized dyes and pigments used in high-performance coatings and imaging technologies.

Basic Information

Item	Details
Product Name	2,5-Difluorobenzoic Acid
CAS No.	2991-28-8
Molecular Formula	C7H4F2O2
Molecular Weight	158.10 g/mol
Synonyms	2,5-Difluorobenzoic Acid; Benzoic acid, 2,5-difluoro-; 2,5-Difluorobenzenecarboxylic acid; 2,5-Difluoro-benzoic acid; α,α,2,5-Tetrafluorotoluene (obsolete); 2,5-Difluorobenzoesäure (German); Acide 2,5-difluorobenzoïque (French)
EINECS	221-062-3

Quality Control

Our 2,5-Difluorobenzoic Acid is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting key parameters such as assay, identity, and impurity profiles. Our quality commitment ensures reliable batch-to-batch consistency and traceability for our global customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	125 - 129 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.