Description

Methyl 4-Trifluoromethylbenzoate is a high-purity aromatic ester derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity and stability imparted by the trifluoromethyl group, enabling the development of compounds with enhanced biological activity and material properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) containing trifluoromethylphenyl groups, particularly for candidates in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the CF3 group improves lipophilicity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and device performance.
• Polymer & Resin Modifier: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions to construct complex biaryl systems.
• Chemical Research & Development: Fundamental starting material in academic and industrial R&D for exploring new fluorinated compounds and reaction pathways.

Basic Information

Item	Detail
Product Name	Methyl 4-Trifluoromethylbenzoate
CAS No.	2967-66-0
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	Methyl p-Trifluoromethylbenzoate; 4-(Trifluoromethyl)benzoic Acid Methyl Ester; Methyl α,α,α-Trifluoro-p-toluate; Benzoic acid, 4-(trifluoromethyl)-, methyl ester; Methyl 4-(Trifluoromethyl)benzoate; p-Trifluoromethylbenzoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Trifluoromethylbenzoate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and GC, NMR, and IR for identity confirmation, to ensure it meets the stringent requirements of our global clientele. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.