Description

Adenylyl-(3'-5')-Uridine 5'-Phosphate is a dinucleoside monophosphate, a fundamental building block in nucleic acid research and synthesis. This compound, CAS NO 2676-45-1, is a critical reagent for studying RNA structure, function, and enzymatic processing. It is essential for biopharmaceutical companies, academic research institutions, and diagnostic developers focused on oligonucleotide therapeutics, molecular biology, and enzymology.

Application

• Oligonucleotide Synthesis: Serves as a key intermediate or reference standard in the chemical and enzymatic synthesis of RNA and mixed-sequence oligonucleotides.
• Enzymology Studies: Used as a substrate or inhibitor to investigate the activity, kinetics, and specificity of nucleotidyltransferases, polymerases, and phosphodiesterases.
• Structural Biology: Employed in NMR and X-ray crystallography studies to determine the three-dimensional structure and dynamics of RNA motifs and protein-RNA complexes.
• Diagnostic Probe Development: Acts as a component in the design and development of high-specificity probes for pathogen detection and genetic analysis.
• Biochemical Research: Utilized in metabolic pathway studies and as a tool compound to explore nucleotide signaling and recognition events.
• Pharmaceutical Reference Standard: Provides a characterized standard for quality control and regulatory compliance in the production of nucleic acid-based active pharmaceutical ingredients (APIs).

Basic Information

Item	Details
Product Name	Adenylyl-(3'-5')-Uridine 5'-Phosphate
CAS No.	2676-45-1
Molecular Formula	C19H23N7O14P
Molecular Weight	604.40 g/mol
Synonyms	ApU; Adenyluridylic Acid; 3'-5'-Adenylyluridine Phosphate; Adenosine(3'→5')uridine Monophosphate; pA-U; AU Dinucleotide; Adenylyluridine Phosphate; 5'-O-Phosphonatoadenylyl-(3'→5')-uridine
EINECS	Contact for details

Quality Control

Our Adenylyl-(3'-5')-Uridine 5'-Phosphate is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with lot-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Extinction Coefficient	Provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.