Description

3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate (DAHP) is a critical phosphorylated seven-carbon sugar acid intermediate in the shikimate pathway. This compound is essential for the biosynthesis of aromatic amino acids and numerous secondary metabolites in plants and microorganisms. It is primarily utilized by researchers and manufacturers in the fields of biochemistry, metabolic engineering, and pharmaceutical development to study and manipulate biosynthetic routes.

Application

• Biochemical Research: A key substrate for studying the shikimate pathway, enzyme kinetics (DAHP synthase), and feedback inhibition mechanisms.
• Metabolic Engineering: Used in the development and optimization of microbial strains for the overproduction of aromatic compounds like L-phenylalanine, L-tyrosine, and L-tryptophan.
• Pharmaceutical Intermediates: Serves as a precursor in the research and potential synthesis of complex natural products and drug candidates derived from aromatic amino acids.
• Enzyme Assay Development: Employed as a standard or reagent in high-throughput screening assays for inhibitors of the shikimate pathway, relevant to herbicide and antimicrobial discovery.
• Educational Reference Standard: Used in academic laboratories for teaching advanced concepts in intermediary metabolism and biosynthesis.

Basic Information

Product Name	3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate
CAS No.	2627-73-8
Molecular Formula	C7H13O10P
Molecular Weight	312.15 g/mol
Synonyms	DAHP; 3-Deoxy-D-arabino-heptulosonic acid 7-phosphate; 3-Deoxy-D-arabino-heptulosonate 7-phosphate; (2R,3S,4R,5R)-2,3,4,5-Tetrahydroxy-7-oxoheptanoic acid 7-(dihydrogen phosphate); 3-Deoxy-D-manno-octulosonate 8-phosphate analog; Phospho-3-deoxy-D-arabino-heptulosonate; KDO 8-P analog; Shikimate pathway intermediate 1
EINECS	220-102-8

Quality Control

Our 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate is produced under stringent conditions to ensure high purity and batch-to-batch consistency for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) providing specifications for assay, optical rotation, and related substances is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.