Description

2'-Deoxyguanosine-5'-Triphosphoric Acid, Disodium is a high-purity nucleotide essential for life science research and diagnostic applications. This compound serves as a critical building block for DNA synthesis, making it indispensable for molecular biology workflows. It is primarily utilized by researchers and manufacturers in the biotechnology, pharmaceutical, and molecular diagnostics industries for applications such as PCR, DNA sequencing, and enzyme studies.

Application

• Polymerase Chain Reaction (PCR): Acts as one of the four essential dNTPs for DNA amplification.
• DNA Sequencing: Used as a substrate in Sanger sequencing and next-generation sequencing (NGS) platforms.
• Enzyme Kinetics Studies: Serves as a substrate for studying the activity of DNA polymerases, kinases, and other nucleic acid-modifying enzymes.
• Synthesis of Modified Oligonucleotides: A key raw material for the enzymatic synthesis of labeled or modified DNA probes and primers.
• Biochemical Assay Development: Employed in the development of diagnostic kits and high-throughput screening assays.
• Cell Culture & Virology Research: Used in studies involving viral replication and cellular metabolism.

Basic Information

Item	Details
Product Name	2'-Deoxyguanosine-5'-Triphosphoric Acid, Disodium
CAS No.	2564-35-4
Molecular Formula	C10H13N5Na2O13P3
Molecular Weight	551.12 g/mol
Synonyms	dGTP, Disodium salt; 2'-Deoxyguanosine-5'-triphosphate disodium salt; Deoxyguanosine triphosphate disodium; dGTP-Na2; Guanosine, 2'-deoxy-, 5'-(tetrahydrogen triphosphate), disodium salt; 5'-dGTP, Na2; dGTP disodium salt hydrate (if applicable)
EINECS	219-902-3

Quality Control

Our 2'-Deoxyguanosine-5'-Triphosphoric Acid, Disodium is manufactured under strict quality control protocols to ensure the high purity and consistency required for sensitive research and in-vitro diagnostic (IVD) applications. Each batch is tested using advanced analytical techniques, including HPLC and spectrophotometry, to confirm identity, potency, and the absence of critical impurities such as other dNTPs or nucleases. A comprehensive Certificate of Analysis (COA) detailing purity, endotoxin levels, and bioburden is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a non-frost-free freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to prevent condensation and moisture ingress. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 98%
pH (1% Solution)	6.5 - 7.5
Water Content (Karl Fischer)	≤ 5.0%
Endotoxin	< 10 EU/mg
Bioburden	< 100 CFU/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.