Description

Cytidylyl-(3'->5')-Guanosine is a defined dinucleotide, specifically a cytidylyl-guanosine phosphodiester, widely utilized as a critical biochemical building block and research standard. Its precise structure makes it an essential tool for studying nucleic acid chemistry, enzyme mechanisms, and oligonucleotide synthesis. This high-purity compound is primarily required by research institutions, diagnostic developers, and pharmaceutical companies engaged in molecular biology, nucleotide analog development, and bioconjugation projects.

Application

• Biochemical Research Standard: Used as a reference compound for calibrating analytical instruments like HPLC and Mass Spectrometry in nucleotide analysis.
• Enzymology Studies: Serves as a specific substrate or inhibitor for studying the activity of nucleases, phosphorylases, and other nucleic acid-metabolizing enzymes.
• Oligonucleotide Synthesis: Acts as a key intermediate or precursor in the chemical and enzymatic synthesis of defined RNA and DNA sequences.
• Diagnostic Reagent Development: Employed in the formulation of probes, primers, and other components for molecular diagnostic assays.
• Pharmaceutical Research: Investigated for the development of nucleotide-based therapeutics, including antiviral and anticancer agents.
• Teaching & Academia: Provides a well-defined model compound for educational purposes in advanced biochemistry and molecular biology courses.

Basic Information

Product Name	Cytidylyl-(3'->5')-Guanosine
CAS No.	2382-65-2
Molecular Formula	C19H25N7O12P
Molecular Weight	574.42 g/mol
Synonyms	3'-5'-Cytidylylguanosine; CpG (in specific context); Cytidylyl(3'-5')guanosine; Cytidyl(3'-5')guanosine; GpC (isomeric form); Cytidine 5'-(trihydrogen diphosphate), 5'-5'-ester with guanosine; Guanosine, 5'-[3-(cytidine 5'-diphosphate)]-
EINECS	Contact for details

Quality Control

Our Cytidylyl-(3'->5')-Guanosine is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous internal standards and can support compliance with relevant pharmacopeial guidelines for research-grade materials upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to prevent degradation. For long-term storage, consider maintaining the product at -20°C under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.