Description

1,2,3,4,5,6-Hexahydro-6,11-Dimethyl-3-(3-Methylbut-2-Enyl)-2,6-Methano-3-Benzazocin-8-Ol Hydrochloride is a complex organic salt of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of novel therapeutic agents targeting the central nervous system. It is primarily required by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of new drug candidates. Its precise chemical structure makes it a valuable building block for medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly for neurological targets.
• Reference Standard: Used as a high-purity calibration standard in analytical chemistry for method development and quality control in pharmaceutical manufacturing.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize the efficacy and safety profiles of new drug candidates.
• Biochemical Research: Utilized in in-vitro and ex-vivo studies to investigate interactions with specific biological receptors or enzymes.
• Process Chemistry Development: Serves as a model compound for scaling up and optimizing synthetic routes in pilot plants.
• Contract Research & Manufacturing (CRAM): Supplied to organizations offering custom synthesis and development services for the pharmaceutical industry.

Basic Information

Product Name	1,2,3,4,5,6-Hexahydro-6,11-Dimethyl-3-(3-Methylbut-2-Enyl)-2,6-Methano-3-Benzazocin-8-Ol Hydrochloride
CAS No.	2276-52-0
Molecular Formula	C20H29NO·HCl
Molecular Weight	335.91 g/mol
Synonyms	8-Hydroxy-6,11-dimethyl-3-(3-methyl-2-butenyl)-2,6-methano-3-benzazocine Hydrochloride; 2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-, hydrochloride; 3-(3,3-Dimethylallyl)-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol Hydrochloride; U-50488 Hydrochloride; U-50488H; trans-(±)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide Hydrochloride (related structural class); Benzazocine derivative hydrochloride; Research compound 2276-52-0.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing results for key parameters such as assay, related substances, and residual solvents. We adhere to cGMP (current Good Manufacturing Practice) principles where applicable to support our clients' regulatory requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.