Description

Clorexolone is a synthetic organic compound belonging to the class of diuretics, specifically a sulfonamide derivative. This high-purity active pharmaceutical ingredient (API) is valued for its precise pharmacological activity and consistent quality in pharmaceutical manufacturing. It is primarily utilized by pharmaceutical companies and research institutions engaged in the development and production of diuretic medications and related therapeutic agents.

Application

• Pharmaceutical API: Primary use as the active ingredient in the formulation of prescription diuretic medications.
• Research Chemical: Used in biochemical and pharmacological research to study renal function, electrolyte balance, and diuretic mechanisms of action.
• Reference Standard: Serves as a high-purity analytical standard in quality control laboratories for method development and validation.
• Intermediate Synthesis: Can be utilized as a key intermediate in the synthesis of more complex pharmaceutical molecules or analogs.

Basic Information

Product Name	Clorexolone
CAS No.	2127-01-7
Molecular Formula	C14H11ClN2O3S
Molecular Weight	322.76 g/mol
Synonyms	6-Chloro-2-cyclohexyl-1,2,3,4-tetrahydro-4-oxo-3-phthalazinesulfonamide; 6-Chloro-2-cyclohexyl-3,4-dihydro-1H-phthalazine-4-one 2-sulfonamide; NSC 49128; Chlorexolone; Clorexolonum; 3,4-Dihydro-6-chloro-2-cyclohexyl-4-oxo-1(2H)-phthalazinesulfonamide
EINECS	218-340-8

Quality Control

Our Clorexolone is manufactured under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical intermediates and APIs. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via HPLC and other pharmacopeial methods. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.