Description

n-[4-(Trifluoromethyl)Phenyl]-2-Fluorobenzamide is a high-purity fluorinated aromatic amide compound, serving as a critical advanced intermediate in modern chemical synthesis. Its value lies in its unique molecular structure, which incorporates both trifluoromethyl and fluorine substituents to impart desirable properties like enhanced metabolic stability and lipophilicity in target molecules. This compound is essential for research and development laboratories, pharmaceutical companies, and agrochemical manufacturers engaged in creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, anti-inflammatory agents, and CNS-active compounds.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the production of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Synthesis Reagent: Employed in cross-coupling reactions, amide bond formation, and as a scaffold for constructing more complex fluorinated heterocycles in organic chemistry.
• Biochemical Tool Compound: Utilized in biochemical assays and as a probe in life science research to study protein-ligand interactions and enzyme mechanisms.

Basic Information

Product Name	n-[4-(Trifluoromethyl)Phenyl]-2-Fluorobenzamide
CAS No.	2053-96-5
Molecular Formula	C14H9F4NO
Molecular Weight	283.22 g/mol
Synonyms	2-Fluoro-N-[4-(trifluoromethyl)phenyl]benzamide; N-(4-Trifluoromethylphenyl)-2-fluorobenzamide; 2-Fluoro-N-(alpha,alpha,α-trifluoro-p-tolyl)benzamide; 2-Fluorobenzoic acid (4-trifluoromethyl)anilide; 2-Fluoro-N-(4-(trifluoromethyl)phenyl)benzamide; Benzamide, N-[4-(trifluoromethyl)phenyl]-2-fluoro-; 2053-96-5; p-Trifluoromethyl-2-fluorobenzanilide
EINECS	Contact for details

Quality Control

Our production of n-[4-(Trifluoromethyl)Phenyl]-2-Fluorobenzamide adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and precise control of residual solvents and heavy metals. We provide detailed Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications. Our facilities operate under cGMP principles where applicable, ensuring consistent quality for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.