Description

3-(Pentafluorophenyl)Propionic Acid is a high-value fluorinated aromatic building block characterized by its reactive carboxylic acid group and electron-deficient pentafluorophenyl ring. This compound matters for its role in synthesizing advanced materials and active pharmaceutical ingredients (APIs), where its unique fluorine substitution pattern imparts enhanced stability, lipophilicity, and metabolic resistance. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty materials industries for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials, enhancing charge transport and stability.
• Polymer Modification: Incorporated as a monomer or cross-linking agent to create specialty polymers with improved chemical resistance and surface properties.
• Organic Synthesis Building Block: Utilized in coupling reactions (e.g., amide formation, esterification) to introduce the pentafluorophenyl moiety into more complex molecular architectures.
• Catalyst & Ligand Preparation: Acts as a starting material for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	3-(Pentafluorophenyl)Propionic Acid
CAS No.	2002-94-0
Molecular Formula	C9H5F5O2
Molecular Weight	240.13 g/mol
Synonyms	3,4,5,6,7-Pentafluorohydrocinnamic Acid; Pentafluorohydrocinnamic Acid; 3-(Perfluorophenyl)propanoic Acid; 3-(2,3,4,5,6-Pentafluorophenyl)propionic Acid; β-(Pentafluorophenyl)propionic Acid; Pentafluorophenylpropionic Acid; 2002-94-0; NSC 404058
EINECS	Contact for details

Quality Control

Our 3-(Pentafluorophenyl)Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with customer specifications. Certificates of Analysis (COA) detailing all test results are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	95 - 100 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.