Description

3-(Pentafluorophenyl)Propionic Acid is a specialized fluorinated aromatic carboxylic acid, serving as a critical building block in advanced organic synthesis. Its unique pentafluorophenyl group imparts distinct electronic and steric properties, making it invaluable for creating high-performance materials and active pharmaceutical ingredients. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries seeking to develop novel compounds with enhanced stability and bioactivity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of protease inhibitors and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms contribute to improved metabolic stability and efficacy.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated components in electronic display materials, enhancing charge transport and thermal stability.
• Polymer Modification: Employed to introduce fluorinated aromatic side chains into polymers, improving chemical resistance and surface properties.
• Ligand & Catalyst Development: Serves as a backbone for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Diagnostic Reagents: Utilized in the synthesis of fluorinated probes and tags for biomedical imaging and assay development.

Basic Information

Product Name	3-(Pentafluorophenyl)Propionic Acid
CAS No.	2002-92-8
Molecular Formula	C9H5F5O2
Molecular Weight	240.13 g/mol
Synonyms	Pentafluorophenylpropionic Acid; 3-(Perfluorophenyl)propanoic Acid; 2-(2,3,4,5,6-Pentafluorophenyl)acetic Acid (common misnomer); β-(Pentafluorophenyl)propionic Acid; 3-(C6F5)CH2CH2COOH; Pentafluorohydrocinnamic Acid; NSC 163082; 2002-92-8
EINECS	Contact for details

Quality Control

Our 3-(Pentafluorophenyl)Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). As a strong acid/organic solvent, it should be kept away from incompatible materials such as strong bases and oxidizing agents. Use appropriate corrosion-resistant containers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	95 - 100 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.