Description

4-Hydroxy-3-Trifluoromethylbenzoic Acid is a versatile fluorinated aromatic building block of significant commercial interest. Its unique structure, combining a carboxylic acid group with a trifluoromethyl substituent on a phenolic ring, makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients. This compound is essential for R&D and production in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to incorporate fluorine's beneficial properties into their molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in areas like anti-inflammatory and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated monomers used in high-performance liquid crystal displays (LCDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to improve chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: A valuable starting material or coupling agent in complex organic synthesis for academic and industrial research.
• Dye & Pigment Intermediate: Used in the manufacture of specialized fluorinated dyes and pigments.

Basic Information

Product Name	4-Hydroxy-3-Trifluoromethylbenzoic Acid
CAS No.	239-68-9
Molecular Formula	C8H5F3O3
Molecular Weight	206.12 g/mol
Synonyms	3-(Trifluoromethyl)-4-hydroxybenzoic acid; 4-Hydroxy-3-(trifluoromethyl)benzoic acid; Benzoic acid, 4-hydroxy-3-(trifluoromethyl)-; 2-Hydroxy-5-carboxybenzotrifluoride; α,α,α-Trifluoro-4-hydroxy-m-toluic acid; 3-Trifluoromethyl-4-hydroxybenzoic acid; 4-Hydroxy-α,α,α-trifluoro-m-toluic acid
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-3-Trifluoromethylbenzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for use in sensitive applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	210°C - 215°C
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.