Description

Benzoic Acid, 4-Fluoro-3-(Fluorosulfonyl)- is a high-value, multi-functional aromatic building block featuring both fluorine and sulfonyl fluoride substituents. This unique structure makes it a critical intermediate for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), particularly in the development of sulfonamide-based compounds. It is essential for R&D and production in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorinated sulfonyl motifs.

Application

• Pharmaceutical Intermediate: Key precursor for synthesizing novel sulfonamide drugs, including kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Building block for creating advanced herbicides and fungicides with enhanced activity and selectivity.
• Material Science: Used in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research: Valuable reagent in medicinal chemistry and process development for introducing the fluorosulfonyl group.
• PET Tracer Development: Potential precursor for fluorine-18 labeled compounds used in positron emission tomography.
• Cross-Coupling Reactions: Serves as an electrophilic partner in Suzuki-Miyaura and other metal-catalyzed couplings.

Basic Information

Product Name	Benzoic Acid, 4-Fluoro-3-(Fluorosulfonyl)-
CAS No.	1934460-95-3
Molecular Formula	C7H4F2O4S
Molecular Weight	222.17 g/mol
Synonyms	4-Fluoro-3-(fluorosulfonyl)benzoic acid; 3-(Fluorosulfonyl)-4-fluorobenzoic acid; 4-Fluoro-3-fluorosulfonylbenzoic acid; 2-Fluoro-5-carboxybenzenesulfonyl fluoride; Benzoic acid, 4-fluoro-3-(fluorosulfonyl)-; 5-Carboxy-2-fluorobenzenesulfonyl fluoride
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 4-Fluoro-3-(Fluorosulfonyl)- is manufactured under strict quality management systems. Each batch is analyzed to ensure high purity and consistency, with specifications tailored to meet the rigorous demands of pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.