Description

L-Carbidopa-3', 4'-Diphosphate is a high-purity, phosphorylated derivative of the established pharmaceutical intermediate L-Carbidopa. This specialized compound is critical for advanced research and development in medicinal chemistry, particularly in the synthesis of novel prodrugs and targeted therapeutic agents. It serves as a key building block for pharmaceutical companies and research institutions focused on neurology and metabolic disorders.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel prodrugs and active pharmaceutical ingredients (APIs) targeting neurological conditions.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of compounds with enhanced bioavailability or targeted delivery.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to dopamine metabolism and phosphate transfer processes.
• Reference Standard: Employed as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Process Development: Utilized in scaling up and optimizing synthetic routes for complex drug molecules within R&D and pilot plant settings.

Basic Information

Product Name	L-Carbidopa-3', 4'-Diphosphate
CAS No.	1907685-82-8
Molecular Formula	C10H14N2O10P2
Molecular Weight	408.17 g/mol
Synonyms	(2S)-3-(3,4-Bis(phosphonooxy)phenyl)-2-methylalanine; L-α-Methyl-3,4-bis(phosphonooxy)phenylalanine; Carbidopa Diphosphate; (S)-(-)-α-Methyl-3,4-dihydroxyphenylalanine 3',4'-Bis(dihydrogen phosphate); L-α-Methyldopa 3',4'-Diphosphate
EINECS	Contact for details

Quality Control

Every batch of L-Carbidopa-3', 4'-Diphosphate is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.