Description

Methyl 3,4-Difluoro-5-Methoxybenzoate is a high-purity fluorinated benzoate ester, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the precise positioning of fluorine and methoxy substituents, which are essential for modulating the electronic and steric properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, where fluorine atoms enhance bioavailability and stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and liquid crystals with tailored properties.
• Chemical Biology: Employed as a probe or labeling agent in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and process development projects.

Basic Information

Product Name	Methyl 3,4-Difluoro-5-Methoxybenzoate
CAS No.	1806332-46-6
Molecular Formula	C9H8F2O3
Molecular Weight	202.16 g/mol
Synonyms	3,4-Difluoro-5-methoxybenzoic acid methyl ester; Methyl 3,4-difluoro-5-methoxybenzoate; Benzoic acid, 3,4-difluoro-5-methoxy-, methyl ester; 5-Methoxy-3,4-difluorobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3,4-Difluoro-5-Methoxybenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.