Description

2,4-Difluoro-3-Nitrobenzoic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its unique substitution pattern, which facilitates the introduction of both fluorine and nitro functional groups into complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring difluoro and nitro-substituted benzoic acid motifs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging its bioisosteric properties.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysis and organocatalysts.
• Fluorine Chemistry Studies: An important reagent for investigating structure-activity relationships (SAR) and the effects of fluorine atoms in medicinal chemistry.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	2,4-Difluoro-3-Nitrobenzoic Acid
CAS No.	1806313-13-2
Molecular Formula	C7H3F2NO4
Molecular Weight	203.10 g/mol
Synonyms	3-Nitro-2,4-difluorobenzoic Acid; 2,4-Difluoro-3-nitrobenzoic Acid; Benzoic acid, 2,4-difluoro-3-nitro-; 1806313-13-2; 2,4-Difluoro-3-nitro-benzoic acid; 2,4-Difluoro-3-nitrobenzoicacid; SCHEMBL23346827; AKOS040759232
EINECS	Contact for details

Quality Control

Every batch of 2,4-Difluoro-3-Nitrobenzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and scale-up activities. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	<10 ppm
Residue on Ignition	≤0.1%
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.