Description

Methyl 2,4-Dibromo-5-Fluorobenzoate is a high-purity, multi-functional halogenated benzoate ester, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a versatile, reactive scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated aromatic motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine and bromine atoms for enhanced bioactivity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating halogenated aromatic cores used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer Modification: Acts as a monomer or functionalization agent for introducing halogenated benzoate groups into specialty polymers to alter thermal, optical, or solubility properties.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) due to the presence of bromine atoms, enabling rapid diversification of chemical space.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for methodology development and exploring new reaction pathways involving halogenated aromatics.

Basic Information

Product Name	Methyl 2,4-Dibromo-5-Fluorobenzoate
CAS No.	1806306-65-9
Molecular Formula	C8H5Br2FO2
Molecular Weight	311.93 g/mol
Synonyms	2,4-Dibromo-5-fluorobenzoic acid methyl ester; Methyl 2,4-dibromo-5-fluorobenzoate; Benzoic acid, 2,4-dibromo-5-fluoro-, methyl ester; 5-Fluoro-2,4-dibromobenzoic acid methyl ester; Methyl 5-fluoro-2,4-dibromobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 2,4-Dibromo-5-Fluorobenzoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.