Description

5-Chloro-2-Ethoxy-4-Fluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique substitution pattern, which provides a versatile chemical handle for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to build active ingredients and novel chemical entities. The CAS number for this specific compound is 1805820-29-4.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and fungicides, leveraging the fluorine and chlorine substituents for enhanced bioactivity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies.
• Organic Synthesis Reagent: Acts as a versatile carboxylic acid component in coupling reactions (e.g., amide formation, esterification) for creating diverse compound libraries in medicinal chemistry.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and developing novel fluorinated compounds.

Basic Information

Product Name	5-Chloro-2-Ethoxy-4-Fluorobenzoic Acid
CAS No.	1805820-29-4
Molecular Formula	C9H8ClFO3
Molecular Weight	218.61 g/mol
Synonyms	4-Fluoro-5-chloro-2-ethoxybenzoic acid; 2-Ethoxy-4-fluoro-5-chlorobenzoic acid; Benzoic acid, 5-chloro-2-ethoxy-4-fluoro-; 1805820-29-4; 5-Chloro-2-ethoxy-4-fluorobenzoic acid; 4-Fluoro-2-ethoxy-5-chlorobenzoic acid
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-2-Ethoxy-4-Fluorobenzoic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee supply reliability and technical compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.