Description

Methyl 4-Bromo-2-Cyano-6-Fluorobenzoate is a high-purity, multi-functional aromatic ester building block designed for advanced organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated and nitrile-substituted structure enables precise molecular modifications. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic frameworks and fine-tuning the biological activity of target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, anti-cancer agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Serves as a versatile building block for developing next-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the creation of advanced organic materials, including liquid crystals, organic semiconductors, and photoactive polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: An essential substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Methyl 4-Bromo-2-Cyano-6-Fluorobenzoate
CAS No.	1805595-96-3
Molecular Formula	C9H5BrFNO2
Molecular Weight	258.05 g/mol
Synonyms	Methyl 4-bromo-2-cyano-6-fluorobenzoate; 4-Bromo-2-cyano-6-fluorobenzoic acid methyl ester; Benzoic acid, 4-bromo-2-cyano-6-fluoro-, methyl ester; Methyl 4-bromo-6-fluoro-2-cyanobenzoate; 2-Cyano-6-fluoro-4-bromobenzoic acid methyl ester; 4-Bromo-6-fluoro-2-cyanobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 4-Bromo-2-Cyano-6-Fluorobenzoate is produced and tested under a strict quality management system to ensure batch-to-batch consistency and reliability for your critical synthesis workflows. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS analysis, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.