Description

Ethyl 3-Cyano-6-Chloro-2-Fluorobenzoate is a high-value fluorinated aromatic ester building block. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals, particularly those requiring a specific halogenated benzoate core. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides that leverage its halogenated aromatic structure.
• Material Science Research: Used in the development of advanced organic materials, including liquid crystals and polymers with specific electronic properties.
• Chemical Biology Probes: Serves as a starting material for creating fluorescent tags or molecular probes for biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Ethyl 3-Cyano-6-Chloro-2-Fluorobenzoate
CAS No.	1805561-18-5
Molecular Formula	C10H7ClFNO2
Molecular Weight	227.62 g/mol
Synonyms	Ethyl 6-Chloro-2-fluoro-3-cyanobenzoate; 2-Fluoro-6-chloro-3-cyanobenzoic Acid Ethyl Ester; Benzoic acid, 3-cyano-6-chloro-2-fluoro-, ethyl ester; 1805561-18-5; Ethyl 2-fluoro-6-chloro-3-cyanobenzoate; 3-Cyano-6-chloro-2-fluorobenzoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-Cyano-6-Chloro-2-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR, and MS for structural confirmation, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.